Early steps toward understanding neuronal communication
نویسندگان
چکیده
منابع مشابه
Big steps toward understanding dynein
It has been 50 years since dynein was discovered and named by Ian Gibbons as a motor protein that drives cilia/flagella bending (Gibbons, 1963; Gibbons and Rowe, 1965). In the mid-1980s, dynein was also found to power retrograde transport in neurons (Paschal and Vallee, 1987). Subsequently, the primary amino acid sequence of the cytoplasmic dynein heavy chain, which contains the motor domain, w...
متن کاملBig steps toward understanding dynein
Dynein is a microtubule-based molecular motor that is involved in various biological functions, such as axonal transport, mitosis, and cilia/flagella movement. Although dynein was discovered 50 years ago, the progress of dynein research has been slow due to its large size and flexible structure. Recent progress in understanding the force-generating mechanism of dynein using x-ray crystallograph...
متن کاملSteps Toward Understanding Performance in Java
Java's design goals of portability, safety, and ubiquity make it a potentially ideal language for large-scale heterogeneous computing. One of the remaining challenges is to create performance models and associated speci cations and programming constructs that can be used to reason about performance properties of systems implemented in Java.
متن کاملOptical and genetic approaches toward understanding neuronal circuits in zebrafish.
Optical and genetic tools are beginning to revolutionize the studies of neuronal circuits. Neurons can now be labeled with conventional or genetically encoded indicators that allow their activity to be monitored during behavior in intact animals. Laser ablations and genetic inactivation offer ways to perturb activity of specific cells to test their contributions to behavior. These approaches pr...
متن کاملOptical and Genetic Approaches Toward Understanding Neuronal Circuits in Zebrafish1
SYNOPSIS. Optical and genetic tools are beginning to revolutionize the studies of neuronal circuits. Neurons can now be labeled with conventional or genetically encoded indicators that allow their activity to be monitored during behavior in intact animals. Laser ablations and genetic inactivation offer ways to perturb activity of specific cells to test their contributions to behavior. These app...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Opinion in Neurology
سال: 2018
ISSN: 1350-7540,1473-6551
DOI: 10.1097/wco.0000000000000512